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Scientist/Senior Scientist Process Chemistry Development

応募後で応募 求人ID R0067073 掲載日 05/17/2022 Location:Boston, Massachusetts

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Job Description

About the role:

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Scientist/Senior Scientist Process Chemistry Development where you will design and obtain laboratory proof of concept for new, concise synthetic routes to challenging synthetic molecule targets. You will be a part of Process Chemistry Development (PCD) team. PCD is responsible for the development of robust, sustainable, and cost-effective processes for the manufacture of new synthetic molecule pharmaceuticals, along with methods for achieving and controlling high standards of purity and quality. As part of the team, you will seek to discover innovative solutions to manufacturing challenges

How you will contribute:

  • You will leverage their technical skill(s) as an expert within our department to lead projects and initiatives across several therapeutic areas.

  • You will be empowered to push the boundaries of synthetic chemistry to innovate in drug development.

  • Design and obtain laboratory proof of concept for new, concise synthetic routes to challenging synthetic molecule targets

  • Oversee external research and manufacturing partners.

  • Collaborate with other Pharmaceutical Sciences colleagues to develop strategic plans for delivering clinical supplies to support ongoing trials.

  • Work in a collaborative and empowering environment on stimulating scientific and technical problems.

  • Responsible for process design to meet the requirements of product development.

  • Make independent contributions to complex/multiple projects or functional area through leading or influencing others.

  • Use understanding of project timelines and big picture (e.g., impact on resources, legal, IP, across functions in Pharm Sci) to plan and coordinate with cross functional peers and evaluate impact of decisions across CMC and other development functions.

  • Responsible for understanding how to weigh and assess technical risk associated with decisions by initiating projects with technical risk.

  • Provide feedback to the CMC team regarding potential manufacturing issues and resolution.

  • Proactively affect resolution of issues during or resulting from manufacturing.

  • May prepare and coordinate completion of technology transfer documentation, CMC sections of regulatory documents, or validation plans and reports within expertise for review.

  • Expected to influence or assist initiatives related to driving scientific and technical improvement within own function and may also participate in scientific initiatives cross functionally.

  • Coordinate cross-functional team and resolutions, predominately in scientific/technical challenges.

  • Expected to have sufficient expertise in multiple technologies within their functional area and recognized/developing as a technical leader/resource by the group, in specific area(s).

  • Develop the ability to define more complex/novel approaches and methodologies to solving complex technical challenges

  • Proactively identifies vendors and builds relationships to gain access to technologies to deliver on pipeline goals.

  • May manage key vendor relationships across multiple projects.

Minimum Requirements/Qualifications:

  • Bachelor's degree in chemistry, engineering, or related pharmaceutical science and 8+ years (11+ years preferred for Senior Scientist level) relevant industry experience

  • Masters degree in chemistry, engineering or related pharmaceutical science; 6+ years (9+ years preferred for Senior Scientist level) relevant industry experience

  • PhD in chemistry; 0+ years (3+ years preferred for Senior Scientist level) relevant industry experience

  • knowledge of synthetic organic chemistry

  • Experience in CMC pharmaceutical development for active pharmaceutical ingredients under cGMP's

  • Experience working in a multi-disciplinary team environment

  • You will have previous experience contributing to regulatory filings and management of contract facilities (CROs and CMOs)

What Takeda can offer you:

  • Comprehensive Healthcare: Medical, Dental, and Vision

  • Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs and company match of charitable contributions

  • Family Planning Support

  • Flexible Work Paths

  • Tuition reimbursement

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.


Boston, MA

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Time Type

Full time