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Senior Scientist, Statistical Genetics

応募後で応募 求人ID R0035120 掲載日 06/15/2021 Location:Boston, Massachusetts; San Diego, California

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Senior Scientist, Statistical Genetics in our Cambridge, MA or San Diego, CA office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.


We are looking for an experienced statistical geneticist to join a dynamic and highly collaborative team of scientists to advance drug discovery and development. The successful candidate will lead human genetics efforts, using publicly available and proprietary data, to advance target identification, safety assessment and population stratification in various disease areas. As part of her/his responsibilities, the incumbent will have the opportunity to contribute to external collaborations to link genetic data to longitudinal phenotypic data from diverse populations. The successful candidate will closely work with colleagues in various functions across the organization, and will have the unique opportunity to contribute to go-no go decisions across Takeda’s drug discovery and development pipeline. 


  • Establish an influential and collaborative role within biology and disease-oriented project teams by contributing to the design, analysis and interpretation of genetic studies to inform target identification, safety assessment and population stratification

  • Work with a community of statistical geneticists to implement a human genetics roadmap and strategy.

  • Work collaboratively with data scientists and data engineering groups to enhance integrative analytic pipelines

  • Establish and lead external collaborations to implement emerging technologies and/or interrogate relevant biomedical datasets with in-depth genetic and health information

  • Prepare and present comprehensive technical or project reports to internal and external audiences


  • PhD in computational biology, bioinformatics or similar discipline with 5+ years of postdoctoral experience in human genetics research.

  • Solid experience with GWAS/eQTL/pQTL analyses, fine-mapping and colocalization, WES/WGS sequencing data analyses, and rare variants statistical analyses required.

  • Experience with phenotype ontologies, Mendelian randomization, pathway-based approaches, multivariate analyses, polygenic risk score analyses, machine learning and/or quantitative analysis of medical imaging data desired.

  • Strong scientific understanding of molecular biology and genomics, and ability to interpret genetic findings in disease context

  • Familiarity with pharmaceutical R&D processes and one or more diseases areas of interest of Takeda (rare diseases, neuroscience, gastroenterology and immunology) desired 

  • Excellent communication, presentation and interpersonal skills

  • Independent, highly collaborative with ability to work in cross-functional and diverse team environment

  • Solid knowledge of Unix, command lines interfaces, and fluency in common scripting and/or programming language (e.g. R, Python, Perl, Java, C/C++)

  • Experience with parallel computing and cloud computing


  • Cambridge, MA, USA  or San Diego, CA


  • Relevant travel


  • 401(k) with company match and Annual Retirement Contribution Plan

  • Tuition reimbursement

  • Company match of charitable contributions

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs

This job posting excludes CO applicants

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Boston, MA

San Diego, CA

Worker Type


Worker Sub-Type


Time Type

Full time