2026 U.S. Summer Internship Program: PBPK (Physiologically Based Pharmacokinetic Modeling) Intern

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Job Description

Drug Metabolism, Pharmacokinetics and Modeling (DMPK&M) is a group within the Quantitative Pharmacology and Translational Sciences function responsible for supporting drug discovery and development

How You Will Contribute:

As a PBPK Modeling Intern, under supervision, you will have the opportunity to…

• Sharpen skills in PBPK modeling software like Simcyp and GastroPlus

• Collaborate with DMPK&M colleagues to identify data requirements for model development, and strategies for model application and use

• Apply modeling for prediction of drug-drug interactions (DDI)
  

Internship Development Opportunities:

• Practice and improve presentation skills

• Learn modeling approaches to solve problems in drug development
  

Job Requirements:

• This position will be hybrid (1-3 days in office), out of the Cambridge, MA location

• Must be enrolled in a Ph.D program in drug metabolism and pharmacokinetics, quantitative pharmacology, clinical pharmacology, toxicology, pharmacometrics, biomedical engineering, pharmaceutical sciences or another related field.

• Must have prior experience with PBPK modeling (Simcyp preferred).

• Be acquainted with standard techniques of model training, validation, and characterization.

• Strong training and understanding of the concepts of drug metabolism and pharmacokinetics of small molecules, biochemical aspects of drug metabolism enzymes and transporters, and various in vitro assays conducted to assess DDI potential

• Track record of publication and / or conference presentations

• Exceptional interpersonal, verbal communication and writing skills

• Good organizational and planning skills

• Proven record of accomplishment of teamwork, adaptability, innovation, initiative, and integrity

• Strong quantitative, analytical and problem-solving skills

• Global mindset to grow in a diverse work environment
  

Internship Eligibility

• Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship 

• Must be currently enrolled in a degree program graduating December 2026 or later 

• The internship program is 10-12 weeks depending on the two start dates (May 26th-August 14th or June 15th- August 21st)  

• The intern must be able to commit to one of these time frames  

• Able to work full time 40 hours a week during internship dates  

• Takeda does not provide a housing stipend or relocation support for the U.S Summer Internship Program 

Program Highlights:

• Hands-on experience with real projects and responsibilities 

• Dedicated mentorship program pairing interns with experienced professionals 

• Networking opportunities with industry professionals and fellow interns 

• Internship events focused on professional and skills development  

• Exposure to multiple business areas or departments within a Pharmaceutical Organization 

Applications will be accepted between October 31st- November 16th

For Location:

Boston, MA

U.S. Hourly Wage Range:

$21.00 - $46.00

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Paid Intern (Fixed Term) (Trainee)

Time Type

Full time

Job Exempt

No

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