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Job Description

About the role

The Head of PMO provides strategic business and technical leadership for a high‑priority, complex, and cross‑functional project portfolio in support of site‑level strategic initiatives. This role is accountable for overall project portfolio performance, including milestone adherence, resource optimization, and financial outcomes, and serves as a key liaison between site leadership, functional partners, and internal and external stakeholders. The Head of PMO embeds project management as a core capability across the organization, driving disciplined execution, transparency, and continuous improvement.

How you will contribute

Project & Portfolio Management

• Lead the Project Management Office (PMO) and directly manage PMO staff.

• Drive site‑level strategic planning for capital and non‑capital projects.

• Partner with site and enterprise leadership to align portfolio priorities, resource allocation, and communications.

• Own facility‑level milestone hit rate and overall portfolio performance.

• Champion and lead cultural transformation in project management maturity.

• Establish and maintain critical business processes to ensure excellence in project execution.

• Participate in project evaluation and feasibility assessments.

• Provide clear direction on project requirements to meet external customer and internal stakeholder expectations.

• Establish and maintain robust project governance, including portfolio reviews and executive updates.

• Ensure consistent application of Takeda’s Project Management Methodology across all projects.

• Approve key project deliverables and confirm readiness for project close‑out.

• Integrate Capital Projects teams with PMO methodologies, ensuring alignment and consistent execution standards.

• Serve as a subject matter expert for SPOT (Single Point of Truth), Takeda’s internal project information system.

Risk Management & Issue Resolution

• Lead the organization’s approach to project and program risk management.

• Make informed decisions on acceptable risk in situations with significant project or program impact.

• Proactively identify, remove, or mitigate barriers to execution.

• Anticipate potential conflicts and implement proactive resolution strategies.

Financial Management

• Provide financial analysis and business justification for new projects and programs.

• Manage the project OPEX budget, including forecasting and monthly reporting.

Administration & Governance

• Act as a champion of PMO processes, recognizing the critical impact of project outcomes on overall business success.

• Define, implement, and manage project and program structures and performance metrics from initiation through scale‑up.

• Ensure effective linkage between portfolio data, project prioritization, and governance processes.

• Drive continuous improvement in the organization’s ability to execute projects from concept through commercial production.

Communication & Leadership

• Communicate effectively and influence key stakeholders, including site leadership, capital project teams, and finance partners.

• Navigate ambiguity by bringing clarity, structure, and disciplined execution.

• Inspire confidence and lead change through a combination of technical expertise, strong leadership presence, and change management capability.

What you bring to Takeda

Education & Experience

• Bachelor’s degree required; Master’s degree preferred.

• Degree in Engineering or a Science‑related discipline preferred.

• Minimum of 8–10 years of progressive project management experience.

• PMP, IPMA, or equivalent project management certification.

Qualifications

• Strong knowledge of cGMP manufacturing environments.

• Demonstrated ability to lead, influence, and drive organizational change.

• Proven decision‑making, technical problem‑solving, and analytical skills.

• Agile mindset with a focus on continuous improvement.

• Strong collaboration skills with the ability to work cross‑functionally and optimize resource utilization.

Important Considerations:

At Takeda, our patients rely on us to deliver quality products. As a result, we must follow strict rules in our manufacturing facilities to ensure we are not endangering the quality of the product. In this role:

Physical Demands:

• In general, the position requires a combination of sedentary work and walking throughout the facility.

Other / Travel Requirements:

• May occasionally be required to wear personal protective equipment (PPE) and other clean room garments.  This may include safety shoes, safety glasses, aprons, face shields, lab coats, full body gowns, booties, hair nets and gloves and hearing protection.  Removal of makeup and jewelry would also be required at times. 

• Able to work more than 8 hours a day or 40 hours a week as required.

More about us:

At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Empowering our people to shine:

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

USA - CA - Thousand Oaks - Rancho Conejo

U.S. Base Salary Range:

$153,600.00 - $241,340.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. 

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. 

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

USA - CA - Thousand Oaks - Rancho Conejo

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

Yes